Work

Paradoxical Effect of Echinocandins across Candida Species In Vitro: Evidence for Echinocandin-Specific and Candida Species-Related Differences

Year: 2007

Type: article

Abstract: Paradoxical growth of some Candida isolates occurs at concentrations above the MIC for echinocandins. In 60 Candida bloodstream isolates from cancer patients (20 C. albicans isolates and 10 isolates each of C. parapsilosis, C. tropicalis, C. krusei, and C. glabrata), paradoxical growth was more frequent with caspofungin than micafungin or anidulafungin, was unrelated to MIC, and was strikingly absent in C. glabrata isolates.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00095-07

Authors: Georgios Chamilos, Russell E. Lewis, Nathaniel Albert, Dimitrios P. Kontoyiannis

Institutions: The University of Texas MD Anderson Cancer Center, University of Houston

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2159338055