Year: 2010
Type: article
Abstract: radiodurans to ionizing radiation (IR) and desiccation is slowly drawing more intense scrutiny. Relative to most other organisms, Deinococcus has a survival advantage measured in orders of magnitude. Exposure to 5 kGy of IR reduces the genome of any bacterium to hundreds of fragments. Deinococcus is no exception. However, Deinococcus seems to take this catastrophe in stride. Over a period of 3– 4 hours, overlapping fragments are spliced together into complete chromosomes, and the cells soon resume normal growth. There is no measurable lethality. Attempts to understand the molecular basis of this
Source: PLoS Genetics
Institutions: University of Wisconsin–Madison, Louisiana State University
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,043
OpenAlex ID: W2053551709