Year: 2013
Type: article
Abstract: Although trait anxiety has been associated with risk decision making, whether it is related to risk per se or to the feeling of the risk, as well as the underlying neurocognitive mechanisms, remains unclear. Using a decision-making task with a manipulation of frame (i.e., written description of options as a potential gain or loss) and functional magnetic resonance imaging, we investigated the neurocognitive relationship between trait anxiety and decision making. The classic framing effect was observed: participants chose the safe option when it was described as a potential gain, but they avoided the same option when it was described as a potential loss. Most importantly, trait anxiety was positively correlated with this behavioral bias. Trait anxiety was also positively correlated with amygdala-based "emotional" system activation and its coupling with the ventromedial prefrontal cortex (vmPFC) when decisions were consistent with the framing effect, but negatively correlated with the dorsal anterior cingulate cortex (dACC)-based "analytic" system activation and its connectivity to the vmPFC when decisions ran counter to the framing effect. Our findings suggest that trait anxiety is not associated with subjective risk preference but an evaluative bias of emotional information in decision making, underpinned by a hyperactive emotional system and a hypoactive analytic system in the brain.
Source: Journal of Neuroscience
Institutions: University of Kentucky, City University of New York, Shenzhen University, Chinese Academy of Sciences, Beijing Normal University, State Key Laboratory of Cognitive Neuroscience and Learning, New York University, University of Edinburgh, Institute of Psychology, Chinese Academy of Sciences, Queens College, CUNY, Icahn School of Medicine at Mount Sinai
Language: English
Subfield: General Decision Sciences
Field: Decision Sciences
Domain: Social Sciences
Open Access status: hybrid
Funders: National Natural Science Foundation of China, Chinese Academy of Sciences, National Institutes of Health, National Key Research and Development Program of China, Institute of Psychology, Chinese Academy of Sciences, National Institute on Aging, National Institute on Drug Abuse, Fogarty International Center, National Center for Research Resources, National Center for Advancing Translational Sciences
Awards: Cellular and Molecular Basis of Brain Aging, G2446054678, G2481881534, G303975689, 情绪与执行功能的相互作用及其神经机制, Role of the amygdala in processing threatening animals and manipulable objects, Kentucky Center for Clinical and Translational Science, G5073799558, CDART - Center for Drug Abuse Research Translation, G5795939169, Kentucky Center for Clinical and Translational Science, Kentucky Center for Clinical and Translational Science, G9000204295
OpenAlex ID: W2064843563