The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases
Year: 2013
Type: article
Abstract: IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).
Source: Nucleic Acids Research
DOI: 10.1093/nar/gkt1115
Authors: Sandra Orchard, Mais Ammari, Bruno Aranda, Lionel Breuza, Leonardo Briganti, Fiona Broackes-Carter, Nancy H. Campbell, Gayatri Chavali, Carol Chen, Noemi del-Toro, Margaret Duesbury, Marine Dumousseau, Eugenia Galeota, Ursula Hinz, Marta Iannuccelli, Sruthi Jagannathan, Rafael Jimenez, Jyoti Khadake, Astrid Lagreid, Luana Licata, Ruth C. Lovering, Birgit Meldal, Anna N. Melidoni, Mila Milagros, Daniele Peluso, Livia Perfetto, Pablo Porras, Arathi Raghunath, Sylvie Ricard-Blum, Bernd Roechert, Andre Stutz, Michael Tognolli, Kim van Roey, Gianni Cesareni, Henning Hermjakob
Institutions: University of Rome Tor Vergata, SIB Swiss Institute of Bioinformatics, European Bioinformatics Institute, University Health Network, University of Arizona, University of British Columbia, National University of Singapore, European Molecular Biology Laboratory, European Molecular Biology Laboratory, Centre National de la Recherche Scientifique, Norwegian University of Science and Technology, University of Geneva, University of Toronto, University College London, Fondazione Santa Lucia, Lyon 1 Université
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,992
Awards: Systems Biology of Stem Cells and Reprogramming, Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application, G6519275499, The integration of biomedical research, describing the biological processes relevant to cardiovascular processes, into Gene Ontology, microRNA and protein interaction databases
OpenAlex ID: W2043764521