Work

Subretinal gene delivery using helper-dependent adenoviral vectors

Year: 2011
Type: article
Abstract: This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects. Since these vectors have a large cloning capacity, they have great potential to extend the success of gene therapy achieved using the adeno-associated viral vector.
Language: English
Subfield: Genetics
Open Access status: gold
Estimated APC paid: $2,890
OpenAlex ID: W2121443197
FWCI: 0.64
Cites: 32
Cited by: 13
Related to: 10