Sustained release dextroamphetamine (15–30 mg but not 30–60 mg) improved retention in patients with cocaine dependence
Year: 2002
Type: article
Abstract: Grabowski J, Rhoades H, Schmitz J , et al. Dextroamphetamine for cocaine-dependence treatment: a double-blind randomized clinical trial. J Clin Psychopharmacol2001 Oct; 21 : 522 –6 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: In patients with cocaine dependence, is sustained release dextroamphetamine more effective than placebo for improving retention? Randomised (allocation concealed*)†, blinded (patients, clinicians, data collectors, and data analysts), placebo controlled trial with 12 weeks of follow up. Department of Psychiatry and Behavioural Sciences at the University of Texas-Houston, Houston, Texas, USA. 128 patients (mean age 36 y, 79% men) with cocaine dependence who were in good medical health without other psychiatric diagnoses (except nicotine dependence), as determined by the Structured Clinical Interview for DSM-IV (SCID). Follow up at study end was {24%}†; all patients were included in the retention analysis. Patients were allocated to dextroamphetamine sulphate, 15 mg for 28 days then doubled to 30 mg for 56 days {n=47} … [1]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2Bclinical%2Bpsychopharmacology%26rft.stitle%253DJ%2BClin%2BPsychopharmacol%26rft.aulast%253DGrabowski%26rft.auinit1%253DJ.%26rft.volume%253D21%26rft.issue%253D5%26rft.spage%253D522%26rft.epage%253D526%26rft.atitle%253DDextroamphetamine%2Bfor%2Bcocaine-dependence%2Btreatment%253A%2Ba%2Bdouble-blind%2Brandomized%2Bclinical%2Btrial.%26rft_id%253Dinfo%253Adoi%252F10.1097%252F00004714-200110000-00010%26rft_id%253Dinfo%253Apmid%252F11593078%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1097/00004714-200110000-00010&link_type=DOI [3]: /lookup/external-ref?access_num=11593078&link_type=MED&atom=%2Febmental%2F5%2F2%2F47.atom [4]: /lookup/external-ref?access_num=000171341500010&link_type=ISI
Source: Evidence-Based Mental Health
DOI: 10.1136/ebmh.5.2.47
Author: Judy Myles
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2048661172