Work

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

Year: 2013

Type: article

Abstract: We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update. This report shows actual examples to explain how these features work, alone and in combination. Some examples incorrectly aligned by MAFFT are also shown to clarify its limitations. We discuss how to avoid misalignments, and our ongoing efforts to overcome such limitations.

Source: Molecular Biology and Evolution

DOI: 10.1093/molbev/mst010

Authors: K. Katoh, D. M. Standley

Institutions: Immunology Frontier Research Center, The University of Osaka, National Institute of Advanced Industrial Science and Technology, The University of Osaka

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,418

Funders: National Institute of Advanced Industrial Science and Technology, Ministry of Education, Culture, Sports, Science and Technology, Agriculture and Agri-Food Canada