Work

The Author Response: Antiproliferation and Redifferentiation in Thyroid Cancer Cell Line by Polyphenol Phytochemicals

Year: 2011

Type: article

Abstract: Thank you for your pointing out some potential discrepancy that some well known thyroid cancer cell lines are not derived from thyroid cell origin in our recent study (1). Schweppe et al. (2) evaluated 40 reported thyroid cancer-derived cell lines using short tandem repeat (STR) and single nucleotide polymorphism (SNP) array analysis. They found some misidentified cell lines in August 2008; the ARO matched the HT-29 colon cancer cell line, and the NPA matched the the M14/MD-MB-435S melanoma cell line (2). In this report, they already admitted that STR or SNP profiling did not provide any information regarding tissue origin and the result of their study was due to cross-contamination of cell lines. Actually we started our study from 2004, four years earlier that the submission date of paper from Schweppe et al. and thyroid

Source: Journal of Korean Medical Science

DOI: 10.3346/jkms.2011.26.10.1398

Authors: Hee Joon Kang, Yeo-Kyu Youn, Mi-Kyung Hong, Lee Su Kim

Institutions: Hallym University, Hallym University Hangang Sacred Heart Hospital, Seoul National University, Seoul National University Hospital, Hallym University Sacred Heart Hospital

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $690