Work

Gamma Oscillation in Schizophrenia

Year: 2011

Type: article

Abstract: Dysfunctional neural circuitry has been found to be involved in abnormalities of perception and cognition in patients with schizophrenia. Gamma oscillations are essential for integrating information within neural circuits and have therefore been associated with many perceptual and cognitive processes in healthy human subjects and animals. This review presents an overview of the neural basis of gamma oscillations and the abnormalities in the GABAergic interneuronal system thought to be responsible for gamma-range deficits in schizophrenia. We also review studies of gamma activity in sensory and cognitive processes, including auditory steady state response, attention, object representation, and working memory, in animals, healthy humans and patients with schizophrenia.

Source: Psychiatry Investigation

DOI: 10.4306/pi.2011.8.4.288

Authors: Yong-Wook Shin, Brian F. O'Donnell, Soyoung Youn, Jun Soo Kwon

Institutions: Asan Medical Center, University of Ulsan, Indiana University Bloomington, Indiana University, Seoul National University

Language: English

Topic: Neural dynamics and brain function

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Institute of Mental Health