Work

Quantized Current Blockade and Hydrodynamic Correlations in Biopolymer Translocation through Nanopores: Evidence from Multiscale Simulations

Year: 2008

Type: article

Abstract: We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent using an innovative multiscale methodology that treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding up the translocation process.

Source: Nano Letters

DOI: 10.1021/nl073251f

Authors: Massimo Bernaschi, Simone Melchionna, Sauro Succi, Maria Fyta, Efthimios Kaxiras

Institutions: Harvard University, Istituto per le Applicazioni del Calcolo Mauro Picone, Sapienza University of Rome

Language: English

Topic: Nanopore and Nanochannel Transport Studies

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, Harvard University

Award: Science of Nanoscale Systems and their Device Applications NSEC