Work

Adhesins in Human Fungal Pathogens: Glue with Plenty of Stick

Year: 2013

Type: review

Abstract: Understanding the pathogenesis of an infectious disease is critical for developing new methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to host tissue is a prerequisite for tissue invasion and infection. Fungal cell wall adhesins involved in adherence to host tissue or abiotic medical devices are critical for colonization leading to invasion and damage of host tissue. Here, with a main focus on pathogenic Candida species, we summarize recent progress made in the field of adhesins in human fungal pathogens and underscore the importance of these proteins in establishment of fungal diseases.

Source: Eukaryotic Cell

DOI: 10.1128/ec.00364-12

Authors: Piet W. J. de Groot, Oliver Bader, Albert D. de Boer, Michael Weig, Neeraj Chauhan

Institutions: University of Castilla-La Mancha, Universitätsmedizin Göttingen, Rutgers New Jersey Medical School, University of Medicine and Dentistry of New Jersey

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2141294282

FWCI: 2.647

Cites: 126

Cited by: 330

Related to: 10