Work

Dynamics of large-scale neuronal networks of the human cortex functional connectivity

Year: 2012

Type: article

Abstract: Spatio-temporally organized low-frequency fluctuations (<0.1 Hz) of blood-oxygen-level-dependent (BOLD) fMRI signal have been intensively investigated as a measure of functional connectivity (FC) between region pairs in the whole brain [1]. Resting state FC is commonly assumed to be shaped by the underlying anatomical connectivity (AC). Furthermore, it has been suggested that the strength, per-sistence, and spatial properties of FC are constrained by the large-scale anatomical structure of the cortex [2]. However, strong resting state FC is often observed between pairs of remote cortical regions, even without apparent direct anatomical connections [3]. Mechanisms generating resting state FC are largely unknown, and it has been contended that indirect connections, interregio-nal distance, and collective effects governed by network

Source: BMC Neuroscience

DOI: 10.1186/1471-2202-13-s1-p117

Authors: Vesna Vuksanović, Philipp Hövel

Institutions: Bernstein Center for Computational Neuroscience Berlin, Technische Universität Berlin, Northeastern University

Language: English

Topic: Functional Brain Connectivity Studies

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,990