Work

Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

Year: 2012

Type: article

Source: Molecular Pharmacology

DOI: 10.1124/mol.112.080531

Authors: Karen J. Gregory, Meredith J. Noetzel, Jerri M. Rook, Paige N. Vinson, Shaun R. Stauffer, Alice L. Rodriguez, Kyle A. Emmitte, Ya Zhou, Aspen C. Chun, Andrew S. Felts, Brian A. Chauder, Craig W. Lindsley, Colleen M. Niswender, P. Jeffrey Conn

Institutions: Monash University, Vanderbilt University Medical Center

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: American Australian Association, National Alliance for Research on Schizophrenia and Depression, National Institutes of Health, Medical Research Council, National Health and Medical Research Council, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Neurological Disorders and Stroke

Awards: G2291296157, Partial Antagonists of mGluR5 for Treatment of Cocaine Addiction, The Vanderbilt Specialized Chemistry Center for Accelerated Probe Development, In Vivo Characterization of mGluR5 Positive Allosteric Modulators, G651285087, Characterization of the molecular biological effects of M1 allosteric modulators, Development of mGIuR5 NAMS for Treatment of Major Depression, G9000215236, Regulation of Signaling by mGluR5, Functions of Metabotropic Glutamate Receptor Subtypes

OpenAlex ID: W2171826008

FWCI: 3.788

Cites: 61

Cited by: 90

Related to: 9