Year: 2025
Type: conference-abstract
Abstract: Macromolecular models are crucial for biomedical research, particularly in drug discovery. However, variations in model quality can impact the reliability of downstream analyses [1, 2]. To advance the evaluation of macromolecular structures, we developed an integrated system for the rapid exploration and comparison of protein structure models derived from cryoEM and crystallography experiments. Our platform seamlessly incorporates multiple resources, including RCSB PDB [3], PDBe [4], PDBj [5], UniProt [6], PDB-REDO [7, 8], EMDB [9], and AlphaFold DB [10]. Currently, the system operates within the PyMOL 3.1 ecosystem, providing an efficient and streamlined workflow for structural analysis.
Source: Structural Dynamics
DOI: 10.1063/4.0001054
Authors: Wojciech Dec, Pawel Rubach, Wladek Minor
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,200
OpenAlex ID: W7101415161