Regenerative Endodontic Success in an Immature Necrotic Tooth With Previously Initiated Root Canal Treatment: a Case Report
Year: 2025
Type: article
Abstract: : Trauma to developing permanent teeth during early childhood can result in pulpal necrosis and arrest of root development. Such events lead to the formation of immature teeth characterized by thin dentinal walls, wide open apices, and incomplete root formation. These anatomical limitations make the teeth structurally weak and highly susceptible to fracture, posing challenges for long-term preservation and function. Traditional treatment modalities, such as calcium hydroxide apexification, though historically popular, offer limited success in promoting continued root development and often require multiple appointments. In contrast, regenerative endodontic procedures (REPs) have emerged as a promising biologically based alternative, designed to reestablish vascularity, promote apical closure, and encourage maturogenesis in necrotic immature teeth. The success of REPs relies on thorough disinfection of the root canal system, the creation of a conducive environment for stem cell migration via scaffold formation (commonly through blood clot induction), and a hermetic coronal seal using biocompatible materials. Mineral trioxide aggregate (MTA) is frequently used due to its superior sealing ability and bioinductive properties. This case report highlights a regenerative endodontic approach in a young adult with a previously traumatized anterior tooth, focusing on both biological success and esthetic preservation. Key Words: Trauma, Immature teeth, Regenerative endodontics, MTA, platelet-rich fibrin
Authors: Medikonda Asmitha Lakshmi, Krishna Chaitanya Popuri, Ravi Kumar Janga, Ramesh Penumaka, Dhana Prakash Gurram, Ratna Kamal Nagelli
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7101448730
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