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The Wnt1G177C mutation impairs fracture healing in mice

Year: 2025

Type: conference-paper

Abstract: Objectives and questions: Wnt1 is essential for bone development and remodeling, with pathogenic variants linked to osteogenesis imperfecta type XV and early-onset osteoporosis. However, their impact on fracture healing remains unclear. This study investigates how the Wnt1G177C/G177C variant affects [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/25dkou229

Authors: Ahmad, Mubashir, Sarwar, Humma, Küppers, Oliver, Bülow, Jasmin, Kölbl, Christoph, Dieterich, Sandra, Haffner-Luntzer, Melanie, Schoppa, Astrid, Yorgan, Timur, Amling, Michael, Schinke, Thorsten, Ignatius, Anita

Institutions: Universität Ulm, University Medical Center Hamburg-Eppendorf

Language: English

Topic: Bone health and osteoporosis research

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7103139538

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