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Bioinformatics and machine learning-based prognostic modeling and immune infiltration revealing key genes associated with Li-Fraumeni syndrome and osteosarcoma

Year: 2025

Type: conference-paper

Abstract: Objectives and questions: Li-Fraumeni syndrome (LFS) is a cancer susceptibility syndrome in which osteosarcoma (OS) accounts for the third highest incidence of LFS malignancies. This study aims to identify the key genes associated with the susceptibility of LFS patients to OS, establish a prognostic [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/25dkou470

Authors: Qiao, Yu, Curto Vilalta, Anna, Yuan, Fahu, von Eisenhart-Rothe, Rüdiger, Hinterwimmer, Florian

Institutions: TUM Klinikum, Technical University of Munich, Jianghan University

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7103140495

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