Spontaneous resolution of dengue maculopathy in an human immunodeficiency virus-infected individual
Year: 2025
Type: article
Abstract: Dengue maculopathy exhibits numerous clinical phenotypes, including foveolitis and outer maculopathy, which involve both ischemic and inflammatory mechanisms.[1] A 36-year-old male patient being treated for high fever (dengue immunoglobulin M positive) was subsequently diagnosed as human immunodeficiency virus infected with a low CD4 count (71 cells/mm3). Seven days postdischarge, blurred vision was noted in the right eye (6/12, N6). Ophthalmoscopy revealed an orangish macular lesion [Figure 1a], and a baseline optical coherence tomography (OCT) revealed a dengue outer maculopathy with hyporeflective, thickened outer retinal layers with subretinal edema [Figure 1b]. He was treated conservatively, and a spontaneous resolution was seen 15 days later with a normal-looking fundus and normal OCT [Figure 1c and d].Figure 1: (a) Fundus photo of the right eye showing an orangish macular lesion. (b) A baseline optical coherence tomography (OCT) revealing a dengue outer maculopathy with hyporeflective, thickened outer retinal layers with subretinal edema. (c) Fundus photo after 15 days revealing spontaneous resolution. (d) OCT is confirmatory of resolutionData availability statement The author had full access to all the data in this report and takes responsibility for the same. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.
Author: Salil A. Mehta
Institution: Lilavati Hospital & Research Centre
Language: English
Topic: Retinal and Optic Conditions
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7103143347