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The impact of chronic stress on osteoarthritis progression in a murine model: A bidirectional relationship

Year: 2025

Type: conference-paper

Abstract: Objectives and questions: Osteoarthritis (OA) is characterized by cartilage degradation and calcification, synovial inflammation, and subchondral bone sclerosis, leading to chronic pain and disabilities. The stress hormones norepinephrine (NE) and cortisol (CORT) play a role in OA pathophysiology by [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/25dkou269

Authors: Rösch, Gundula, Rapp, Anna, Tsai, Pei-Ling, Taheri, Shahed, Kohler, Helena, Mayakrishnan, Ravikumar, Platzer, Hadrian, Moradi, Babak, Schilling, Arndt, Zaucke, Frank, Slattery, David, Jenei-Lanzl, Zsuzsa

Institutions: Goethe University Frankfurt, University Hospital Frankfurt, Universitätsmedizin Göttingen, University of Göttingen, University Hospital Schleswig-Holstein

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7103149908

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