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Efficient Heritability Estimation in Multivariate Generalized Linear Models via Low-Rank Approximations

Year: 2025

Type: conference-paper

Abstract: Introduction: Linear mixed models are widely used in genetics to estimate genetic variance components from SNP data. These models typically assume that phenotypes follow a (multivariate) normal distribution. However, in many practical settings, phenotype distributions deviate from normality, limiting [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/25gmds005

Authors: Grabert, Gordon, Mohammadnejad, Afsaneh, Bonat, Wagner Hugo, von Bornemann Hjelmborg, Jacob, Kacprowski, Tim

Institutions: University of Southern Denmark, Technische Universität Braunschweig, Universidade Federal do Paraná

Language: English

Topic: Genetic and phenotypic traits in livestock

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7103881988

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