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Network-based identification of drugs and drug combinations targeting host dependency factors across multiple pathogens

Year: 2025

Type: article

Abstract: Introduction: The emergence and re-emergence of viral pathogens have the potential to cause life-threatening epidemics, particularly in our increasingly globalized and ecologically challenging world. A critical aspect of pandemic preparedness is the development of effective antiviral therapies, particularly [for full text, please go to the a.m. URL]

DOI: 10.3205/25gmds185

Authors: Oswald, Marcus, Dietz, Andre, Naseri, Mohadeseh, Hiemisch, Alicia, Isewon, Itunuoluwa, Mateo, Mathieu, Ayehunie, Seyoum, Erfle, Holger, Toptan Grabmair, Tuna, Goujon, Caroline, König, Rainer

Institutions: Jena University Hospital, Institut Pasteur, MatTek (Slovakia), Heidelberg University, Technical University of Munich, Centre National de la Recherche Scientifique, Institut de Recherche en Infectiologie de Montpellier

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Funder: European Commission

Award: Antivirus Pandemic Preparedness EuropeAn pLatform

OpenAlex ID: W7103887508

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