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Towards Uniformly Applicable Polygenic Risk Scores: Factors Influencing Cross-Ancestry Prediction Performance

Year: 2025

Type: conference-paper

Abstract: Introduction: Genome-wide association studies (GWAS) aim to investigate the associations between genetic variants and phenotypes. This is especially helpful for the study of complex diseases, for which it is demonstrated that they are highly polygenic. One possible application of GWAS is the calculation [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/25gmds006

Authors: Thoben, Corinna, Dehncke, Daniel, Kacprowski, Tim

Institution: Technische Universität Braunschweig

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7103893857

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