Identification of Degradants of Thermal and Oxidation Stress Studies of Empagliflozin and Linagliptin Tablets by Hplc-pda and Lc-ms Instrumental Techniques
Year: 2025
Type: article
Abstract: Objective of the manuscript is to identify the degradants observed in the thermal and oxidation degradation sample of Empagliflozin and Linagliptin tablets by using LC-MS and HPLC-PDA instrumental techniques. Thermal and oxidation degradation samples were injected in HPLC-PDA and LC-MS instruments. Mass of the degradants were detected by LC-MS technique, which were assigned to the probable structures correlating with the impurities mentioned in the literature. The assigned probable structures for the degradants were confirmed by procuring and confirming by injecting in HPLC-PDA detector and LC-MS instruments.
Author: Bheemi Reddy Ashok Reddy1*, Mukund Reddy Bembadi2, Shiva Krishna Kumari Gudisheva3, Dr. Akuthota Ashok Kumar*4, Dr. Rajesh Vooturi5
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7104902003
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