Alpha Tocopherol as an Adjuvant in Diabetic Patients-extending Benefits Beyond Extraction Socket Healing
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: ABSTRACT Background:Diabetic patients often present with delayed wound healing and increased risk of post-operative complications following dental extractions due to impaired microvascular function, oxidative stress, and altered immune response. Alpha-tocopherol (Vitamin E), a potent lipid-soluble antioxidant, has been shown to reduce oxidative damage and enhance tissue repair. This study aims to evaluate the effectiveness of vitamin E as an adjunct to reduce post operative complications in extraction in diabetic Patients.Materials and Methods :A total of 30 patients were randomly allocated to Group E and Group S. Vitamin E was applied to Gelfoam in extraction socket in Group E, while Group S received Gelfoam with saline. Postoperative pain, incidence of dry socket were evaluated on 3rd day and healing progression were evaluated on 3rd and 7th day using standardized clinical criteria Results: Vitamin E group showed significantly reduced postoperative pain, faster healing, and lower incidence of dry socket compared to control sites and no adverse effects related to Vitamin E application were observed .Conclusion: Intrasocket Vitamin E application appears to be a safe and effective adjunct for improving postoperative outcomes in diabetic patients following tooth extraction, by promoting healing, reducing pain, and minimizing the risk of dry socket. Keywords: Vitamin E; Diabetic patients; extraction; Postoperative complications; Dry socket
Authors: Dr. Pooja Sree chunduru MDS, Dr.P.S.V.P Jatin, Dr. Anu Vattikuti, Dr.Lakshmi Prasanna, Dr. N.Jyothirmai MDS, Dr. K. Radha Sindhuja MDS
Institution: Chiricahua Community Health Centers
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7105803446
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