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Relationship between HbA1c levels and thickness of carotid intima media in prediabetic and diabetic patients

Year: 2025
Type: article
Study design: Observational Study
Abstract: In this study, it was shown that cardiovascular risk can be reduced by controlling risk factors, and this can be achieved by measuring the carotid intima-media thickness (CIMT) and performing follow-up. An increase in atherosclerosis and cardiovascular risk factors is seen in the prediabetic stage, and CIMT measurement may help in preventing complications before developing diabetes and inflammatory processes. Total 89 patients and 40 healthy controls were analyzed to determine the relationship between their mean HbA1c levels, laboratory data, and CIMT in patients with identified chronic diseases. No significant correlation was noted between the mean HbA1c and right and left CIMT in patients with diabetes mellitus. In the prediabetic patient group, the a weak positive and significant correlation was found between mean HbA1c and bilateral CIMT analysis. In conclusion, the risk of atherosclerosis and cardiovascular complications is increased in the prediabetic stage and non-invasive evaluation with treatment and follow-up may prevent complications, especially cardiovascular ones, in the diabetic stage. • Despite the availability of many non-invasive tests that predict atherosclerosis, CIM thickness measurement remains important. • Patients treated for DM, it has been observed that CIM thickness decreases and atherosclerosis is controlled after HbA 1c levels are brought under control following treatment. • Cardiovascular risk increases in prediabetic patients. • Albuminuria levels are associated with the progression of atherosclerosis in diabetic patients.
DOI: 10.1016/j.endmts.2025.100283
Authors: Murat Ay, Alper Sari
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,910
OpenAlex ID: W7105930555
FWCI: 0.649
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Cited by: 1
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