Pathomorphology of Post-COVID Myocarditis
Year: 2025
Type: article
Study design: Observational Study
Abstract: This paper provides an elaborate morphological analysis of myocardial tissue of patients who succumbed to post-COVID myocarditis. It was conducted on 24 autopsy cases that had clinically aggravated symptoms of cardiac injury after they contracted COVID-19 infection. The leading causes of death were infectious cardiomegaly (5 cases), heart failure (4 cases), decompensated myocarditis with arrhythmia (6 cases), pulmonary artery thromboembolism (3 cases) and pulmonary edema (6 cases). Histopathological analysis showed that there were progressive alterative, dystrophic, and necrobiotic changes in the vascular walls of the myocardium, edema, mucoid degeneration and muscle fiber myolysis. Cardiomyocytes necrosis, sarcomere fragmentation, myxomatosis, calcidosis, and formation of lymphocytic thrombi were noted. The typical post-COVID myocarditis pathophysiology was characterized by the diffuse interstitial edema, lymphoid infiltration, and lymphocytic thrombosis of the myocardial veins.
Authors: Sardor Abdusaminovich Shakirov, Ergasheva Zumrad Abduqayumovna, Kritika Singh, Ananta Shrivastava
Institutions: Andijan State Medical Institute, Galgotias University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7108080873
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