Work

First-in-Human Application of Very High-Power Short-Duration RF Ablation for Refractory AVNRT: A Case Report

Year: 2025

Type: article

Abstract: BACKGROUND: Refractory atrioventricular nodal reentrant tachycardia (AVNRT) is a rare condition, but poses a clinical challenge after failed standard ablation. Very high-power, short-duration (vHPSD) radiofrequency (RF) ablation has not yet been explored in slow pathway ablation/modification. CASE SUMMARY: A 61-year-old woman with recurrent AVNRT despite two prior ablations and multiple antiarrhythmics underwent successful slow pathway ablation using a 90-watt, 4-s vHPSD protocol. CARTO-guided mapping localized the presumed slow pathway, followed by several 90 W applications. Transient second-degree AV block (Wenckebach type) occurred and resolved spontaneously. The patient remained arrhythmia-free at 6-month follow-up. CONCLUSIONS: This is the first reported clinical use of 90 W/4 s RF energy for AVNRT. The vHPSD approach may offer an effective alternative for patients with refractory AVNRT.

Source: Life

DOI: 10.3390/life15121834

Authors: Milos Babic, Milosav Tomovic, Dejan Vukajlovic, Vasko Zugic, Aleksandra Grbovic, Masa Petrovic, Milovan Bojic, Aleksandra Nikolic

Institutions: Institut za kardiovaskularne bolesti Dedinje, University of Belgrade

Language: English

Topic: Cardiac Arrhythmias and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137