Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Schizonepeta tenuifolia Briq ( S. tenuifolia ), a perennial plant from the Lamiaceae family, has been used in herbal medicine to treat diseases. Herein, we investigate the biofunctional properties of S. tenuifolia at different harvesting time points. Biofunctional compounds such as rosmarinic acid, pulegone, and menthone from S. tenuifolia extracts were quantified by using high-performance liquid chromatography and gas chromatography–mass spectrometry. The antioxidant activities of S. tenuifolia extracts were measured in vitro using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS), and ferric reducing antioxidant power (FRAP) assays. The total phenolic content was measured in vitro. The S. tenuifolia extracts showed the highest ABTS, FRAP, and total phenolic compound at the full bloom stage (S4) and the highest DPPH activity at the fruiting stage (S6). Rosmarinic acid (RA) peaked at S5 (676.87 μg/g dry weight), with strong correlation to antioxidant activity. The pulegone content was the highest at the spike formation stage (S3), whereas the menthone content peaked at S6. Considering that the antioxidant activity and number of functional compounds in S. tenuifolia vary with harvest time, the optimal harvest periods identified were during the S4 and S5 (fruiting) stages, which maximize the bioactivity, including antioxidant activity and product quality.
Source: ACS Omega
Authors: Yong-Nam Cho, Yun-Sook Kim, Yeong-Bin Kim, Sang-Eun Lee, Sang-Eun Lee, Min-Ji Gang, Se-Hee Jeon, Jae-Young Heo, Sung-Tae Lee, Sung-Tae Lee
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
SDG: Zero hunger
Open Access status: gold
Estimated APC paid: $1,935
Funder: Rural Development Administration
Award: G1424580419
OpenAlex ID: W7108329761