Primary Pulmonary Hodgkin's Lymphoma: a Case of Diagnostic Complexity and Treatment Resistance
Year: 2025
Type: article
Study design: Case Report
Abstract: Primary pulmonary Hodgkin's lymphoma (PPHL) arises from the lymphoid tissue of the alveolar mucosa or peribronchial lymph nodes. PPHL is extremely rare, representing only 1.5–2.4% of all cases of primary pulmonary lymphoma.[1] Its rarity and nonspecific presentation often lead to diagnostic delays. Symptoms such as cough, fatigue, or chest discomfort mimic other pulmonary diseases, complicating clinical evaluation. Here, we present a case of PPHL initially misdiagnosed as granulomatosis with polyangiitis due to overlapping clinical and histopathological findings. This case emphasizes the importance of a multidisciplinary approach and highlights the critical role of thorough histopathological analysis in establishing an accurate diagnosis.
Authors: Radosław Pastuszek, Magdalena Rosiewicz, Karolina Bieńkowska, Aleksandra Pastuszek, Anita Janda, Sylwia Bartolik, Marcin Durowicz, Iwona Górnicka, Jan Drzymała, Urszula Kierepka
Institution: Medical University of Warsaw
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $100
OpenAlex ID: W7108440489