KMT2Ar, but not other high-risk genetics, adversely impacts outcomes in adult patients with relapsed/refractory (R/R) Philadelphia chromosome negative B-cell acute lymphoblastic leukemia (B-ALL) treated with brexucabtagene autoleucel (Brexu-cel)
Year: 2025
Type: conference-abstract
Source: Blood
Authors: Jessica Leonard, Abdullah Ladha, Rawan Faramand, Gregory Roloff, Yannis Valtis, Virginia Tan, Katharine Miller, Amy Zhang, Michael Grunwald, Vamsi Kota, Jacob Boccucci, Matthew Ulrickson, Ali Al-Darobi, LaQuisa Hill, Ibrahim Muhsen, Joshua Sasine, Anjali Advani, Karamjeet Sandhu, Ran Reshef, Marlise Luskin, Evan Chen, Chenyu Lin, Ryan Cassaday, Noam Kopmar, Melhem Solh, Catherine Lee, Silvina Odstrcil Bobillo, Stephanie Tsai, Timothy O'Connor, Talal Hilal, Jae Park, Sumithira Vasu, Evandro Bezerra, Kristen O'Dwyer, Jozal Moore, Eunice Wang, Ross McCauley, Navneet Majhail, Aravind Ramakrishnan, Luke Mountjoy, Shahbaz Malik, Minoo Battiwalla, Paul Shaughnessy, John Mathews, Hrishikesh Srinagesh, Katherine Sutherland, Omer Jamy, Razan Mohty, Muthu Kumaran, Rasmus Hoeg, Caspian Oliai, Georgia Lill, Wendy Stock, Marc Schwartz, Tamer Othman, Divya Koura, Kaitlyn Dykes, Aaron Logan, Michael Daunov, Ken Byrd, Fevzi Yalniz, Veronika Bachanova, Sean Tracy, Punita Grover, Matthew Connor, George Yaghmour, Vivian Irizarry Gatell, Clayton Jackson, Olalekan Oluwole, Bhagirathbhai Dholaria, Noelle Frey, Lori Muffly, Bijal Shah, Ibrahim Aldoss
Institutions: Oregon Health & Science University, University of Southern California, Moffitt Cancer Center, University of Chicago, Memorial Sloan Kettering Cancer Center, Stanford University, Levine Cancer Institute, Augusta University, Banner MD Anderson Cancer Center, Baylor College of Medicine, Cedars-Sinai Medical Center, Cleveland Clinic, City Of Hope National Medical Center, Columbia University Irving Medical Center, Columbia University, Dana-Farber Cancer Institute, Duke University, University of Washington, Fred Hutch Cancer Center, University of Utah, Loyola University Medical Center, The Ohio State University, University of Rochester Medicine, Roswell Park Comprehensive Cancer Center, Sarah Cannon, St David's Medical Center, Colorado Blood Cancer Institute, University of Alabama at Birmingham, University of Arkansas for Medical Sciences, University of California, Davis, University of California, Los Angeles, Ronald Reagan UCLA Medical Center, University of California San Diego, University of California, San Francisco, University Hospitals Seidman Cancer Center, The University of Kansas Cancer Center, University of Kentucky, Markey Cancer Center, University of Minnesota, University of Pennsylvania, The University of Texas Southwestern Medical Center, Vanderbilt University
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W7108453348