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Advancing mRNA-LNP characterization: innovative chromatographic approaches for next-generation therapeutics

Year: 2025

Type: article

Abstract: No single analytical technique can comprehensively characterize complex biomolecules such as mRNA-LNP products. Charlotte Barker (Editor, Vaccine Insights) speaks to Jonathan Maurer (Postdoctoral Researcher, University of Geneva) about critical quality attributes for mRNA-lipid nanoparticle formulations, novel chromatographic methods for integrity and encapsulation efficiency evaluation, and the technical challenges of characterizing large RNA therapeutics.

Source: Vaccine Insights

DOI: 10.18609/vac.2025.040

Author: Jonathan Maurer

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7108483062

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