Work

A first-in-primate In Vivo CRISPR/Cas9 screen in a rhesus macaque model identifies drivers of CAR-T expansion, tissue tropism and persistence

Year: 2025

Type: conference-abstract

Source: Blood

DOI: 10.1182/blood-2025-2329

Authors: Francesca Alvarez Calderon, Marlana Winschel, Smriti Srikanth, Marc Schwartz, Ryan Fleming, Lev Gorfinkel, Rachel Hu, Casey Son, John Doench, Leslie Kean, Ulrike Gerdemann

Institutions: Boston Children's Hospital, Harvard University, Dana-Farber Cancer Institute, Broad Institute

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7108715500

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