Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy syndrome (APECED) is an autosomal recessive disorder characterised by the combination of autoimmune endocrine damage, mucocutaneous candidiasis and ectodermal tissue damage.Case presentation: we report the case of an 18-year-old female patient with APECED syndrome: the abnormalities found are in chronological order: primary hypoparathyroidism, mucocutaneous candidiasis, Addison's disease, Lichen planus, Biermer's anemia and autoimmune ovaritis. Lichen planus was diagnosed clinically and histologically.Conclusion: The occurrence of lichen planus is unusual in this syndrome. In this review, we first review the current knowledge of APECED syndrome and focus on the relationship between APECED syndrome and Lichen planus.
Authors: Moustaghit, Imane, Damoune, Ikram, Chraibi, Abdelmajid
Institution: Université Ibn Zohr
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W7109208123
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