Work

Fishnet-like 2D magnetic nanozyme probe enables ultrasensitive bedside immunodiagnosis of bone infection pathogens

Year: 2025

Type: article

Abstract: ). FGDAI-WGA-ICA completes testing in under 25 min with a visual limit of detection of 10 cells/mL, exhibiting high sensitivity and specificity for the target pathogens. Moreover, validation in a cohort of 83 synovial fluid samples showed high concordance with clinical reference methods, supporting its potential for real-time, bedside diagnosis of bone infections.

Source: Bioactive Materials

DOI: 10.1016/j.bioactmat.2025.11.043

Authors: Chongwen Wang, Changyue Xu, Jiaxuan Li, Ting Wu, Kaijie Guo, Bingjie Wang, Junyan Ai, Limin Ma, Bing Gu, Yuanchen Ma

Institutions: Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Southern Medical University

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,200