Year: 2017
Type: dissertation
Abstract: "This thesis is organized in five parts: introduction, three chapters of experimental work and a general discussion. In the introduction section, major topics necessary for a broad comprehension of this thesis is described. Major aspects about neurodegenerative diseases and (poly)phenols importance in the disease prevention are present. State of art of major cellular models used for studying (poly)phenols role in Parkinson’s disease (PD) is also described. Emphasis to the knowledge gaps of (poly)phenols potential to act inside the brain was considered such as their ability to cross and/or interact with the blood-brain barrier (BBB). Finally, a thesis rational and major work objectives are concluding the introductory section. Part of this section was included in a review published in Current Neuropharmacology.(...)"
Author: Figueira, Inês Margarida Lourenço
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Awards: Instituto de Investigação do Medicamento, Sem título, DECIPHERING THE POTENTIAL OF BLACKBERRY POLYPHENOLS FOR PARKINSON DISEASE: DIGESTION, BLOOD BRAIN BARRIER TRANSPOSITION AND NEUROPROTECTIVE EFFECT, 4462 .: iNOVA4Health - Programa de Medicina Translacional (iBET, CEDOC/FCM, IPOLFG e ITQB), PROGRAMA DOUTORAL EM BIOENGENHARIA: TERAPIAS CELULARES E MEDICINA REGENERATIVA
OpenAlex ID: W7112099583