Microgolf Verwarming en Diëlektrische Karakterisatie voor Flowchemie
Year: 2025
Type: dissertation
Abstract: Microwaves are increasingly being used to intensify organic synthesis reactions and improve their outcome in terms of product purity. However, these improvements were mostly demonstrated on the scale of mL's using commercial equipment that relies on 2.45 GHz irradiation. Even though the advantages of microwave-based heating have been clearly demonstrated, we believe that this is merely the tip of the iceberg, and further significant improvements can be achieved by 1) moving to flow based systems, 2) using optimized signal waveforms (power and frequency) for a given reaction, 3) using reactors that provide multi-dimensional temperature control within the same heating chip. By truly exploring the entire design space available for advanced microwave-based thermal control systems on the microscale, we aim to enable a new scalable generation of flow devices that can generate with the high throughput in a fast and energy efficient manner large chemical compounds libraries.
Source: Lirias (KU Leuven)
Author: Martinic, Matko
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7112406190
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