Clinical, laboratory and histopathological profiles of thyroid carcinoma patients at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from January 2020 to June 2024
Year: 2025
Type: article
Study design: Observational Study
Abstract: Thyroid carcinoma is a malignancy of the thyroid gland and it is the most common endocrine tumor. Globally, thyroid carcinoma ranks 7th in incidence and 24th in mortality, while in Indonesia, thyroid carcinoma ranks 12th among all carcinomas. Therefore, this study aims to determine the clinical, laboratory, and histopathological profiles of thyroid carcinoma patients. This study used a retrospective descriptive method with total sampling technique. The data were collected from medical records of thyroid carcinoma patients at Dr. Soetomo General Academic Hospital from January 2020 to June 2024. A total of 141 thyroid carcinoma patients were enrolled in this research. Most were aged 51-60 years (34.0%) and female (74.5%). The most commonly reported symptoms were a lump in the neck (100%), hoarseness (19.9%), and pain in the lump (15.6%). Nodules were commonly found to be >4 cm (49.6%), predominantly on the right side of the neck (36.9%). Most patients had normal FT4 (66.0%) and TSH levels (61.7%). Most patients had TR5 ultrasound results (44.7%). The most common histopathological type is papillary (91.5%), and stage 1 (47.5%) is the most common stage. Lymph nodes were the most frequent site of metastasis (36.2%). In conclusion, thyroid carcinoma most commonly occurs in patients aged 51-60 years, predominantly female, and the main complaint is a lump in the neck. Most patients have normal laboratory results and TR5 ultrasound results. The most common type is papillary, at stage 1, with the most common metastasis to lymph nodes.
Authors: Maheswari, Arsanti Nabilah, Wironegoro, Rio, Rahniayu, Alphania, Susanto, Hermawan
Institution: Universitas Airlangga
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7114765308
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