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Lipid-regulated assembly mechanisms and functional energetics of the essential bacterial chaperone BamA

Year: 2025

Type: article

Abstract: Bacterial outer membrane β-barrel BamA stability and folding mechanisms are modulated by the outer membrane lipids phosphatidylethanolamine and phosphatidylglycerol, linking β-barrel biophysics with its function as a membrane chaperone.

Source: Chemical Science

DOI: 10.1039/d5sc07027a

Authors: Anjana George, Anusree Mulanthala Raj, Akanksha Gajanan Patil, Varsha Kumari, Radhakrishnan Mahalakshmi

Institution: Indian Institute of Science Education and Research, Bhopal

Language: English

Topic: Lipid Membrane Structure and Behavior

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: Wellcome Trust, Lady Tata Memorial Trust, Department of Biotechnology, Ministry of Science and Technology, India, University Grants Commission, Indian Institute of Science Education and Research Bhopal, Indian Institute of Science Education and Research Mohali, Science and Engineering Research Board

Awards: G1969609579, G4655341832, G8572416517

OpenAlex ID: W7114789637

FWCI: 0.508

Cites: 77

Cited by: 2

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