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Association of matrix metalloproteinases polymorphisms with glaucoma risk, glaucoma phenotype, and response to treatment with selective laser trabeculoplasty or latanoprost

Year: 2025

Type: article

Abstract: In open-angle glaucoma, the increase in intraocular pressure (IOP) is caused by an increased resistance to aqueous humour outflow in the trabecular meshwork. Since genetic variability of matrix metalloproteinase (MMP) genes may influence extracellular matrix remodelling, we investigated their association with glaucoma risk and/or response to treatment. The retrospective part of the study included patients with primary open-angle glaucoma and ocular hypertension (OHT)

Source: DiRROS repository (University of Maribor)

Authors: Atanasovska Velkovska, Makedonka, Goričar, Katja, Blagus, Tanja, Dolžan, Vita, Cvenkel, Barbara

Language: English

Topic: Glaucoma and retinal disorders

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7114825611

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