Work

Diagnostic value of dopamine transporter imaging with SPECT and PET in differentiating Parkinson's disease from atypical parkinsonian syndromes: A systematic review and meta-analysis

Year: 2025

Type: review

Abstract: Parkinson's disease (PD) and atypical parkinsonian syndrome (APS) are both highly disabling neurodegenerative disorders. While they show significant overlap in clinical features, the therapies and prognoses are distinct. The differential diagnosis between PD and APS is challenging and critical for patient management. This study aimed to evaluate the diagnostic accuracy of dopamine transporter (DAT) radionuclide imaging in the differential diagnosis of PD and APS.

Source: Journal of Nuclear Medicine and Molecular Imaging

DOI: 10.65457/jnmmi-2025-0012

Authors: Yiqi Li, Yan Cui, Bulin Du, Shu Wang, Xuena Li, Yaming Li

Institutions: First Hospital of China Medical University, China Medical University

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Natural Science Foundation of China, Department of Education of Liaoning Province