Work

History and progress in viral vector particle size distribution analysis

Year: 2024

Type: article

Abstract: Abi Pinchbeck, Editor, Cell & Gene Therapy Insights, speaks to Steven Berkowitz, Analytical Development Expert, taking a deep dive into the role of analytical ultracentrifugation (AUC) and other methods used in viral vector particle size distribution analysis. They discuss the multi-levels of heterogeneity present in gene therapy products, the history and relevance of AUC as the ‘gold standard’ of molecular characterization, and the up-and-coming tools and developments in the space.

Source: Cell and Gene Therapy Insights

DOI: 10.18609/cgti.2024.180

Author: Steven Berkowitz

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7115560171

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