Nutritional and Metabolic Characteristics of Overweight Women with Polycystic Ovary Syndrome (PCOS): A Case-Control Study
Year: 2025
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: Polycystic Ovary Syndrome (PCOS) is a common cause of menstrual disorders, infertility, and hyperandrogenism, often associated with insulin resistance and an increased risk of metabolic disorders. This study aimed to assess the metabolic and nutritional characteristics of overweight women with PCOS. METHODS: This was a descriptive, cross-sectional, and retrospective case-control study that included 61 overweight women, divided into two groups: 31 women with PCOS and 30 controls without PCOS. Data were gathered through review of the patients' medical records. RESULTS: High blood pressure, type 2 diabetes, dyslipidemia, and metabolic syndrome were significantly more frequent in the PCOS group compared to the control group (p<0.001; p<0.001; p=0.002; and p=<00001, respectively). Eating disorders were more frequently observed in women with PCOS, with a significantly higher occurrence of binge eating behaviors in these patients compared to the control group (p=0.009). The intake of saturated fatty acids was higher in women with PCOS (p=0.01). Regarding micronutrients, intakes of vitamin C and vitamin B1 were significantly lower in PCOS patients (p=0.01 and p=0.04, respectively). However, significantly more prevalent nutrient deficiencies in omega-6 fatty acids (p=0.001), vitamin C (p=0.002), vitamin B1 (p=0.03), vitamin B3 (p=0.003), vitamin B6 (p=0.03), and iron (p=0.02) were noted in the PCOS group. CONCLUSIONS: Women with PCOS exhibit a higher occurrence of cardio-metabolic risk factors and multiple nutritional deficiencies. Early and personalized management is crucial to improve their long-term health outcomes and quality of life.
Source: La Tunisie Médicale
Authors: Kamilia Ounaissa, Sana Khamassi, Taieb Ach, Ramla Mizouri, Amel Gamoudi, Awatef Kacem, Faten Mahjoub, Haifa Abdesselem, Emna Bornaz, Yosra Hasni, Henda Jamoussi, Chiraz Amrouche
Institution: Hôpital Farhat Hached
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7115602856