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FlowCyPy: a high-fidelity flow cytometry simulation framework for extracellular vesicle analysis

Year: 2025

Type: conference-paper

Abstract: FlowCyPy is an open-source simulation framework integrating physics-based fluidic, optical, and electronic models to predict extracellular vesicle detection in flow cytometry, enabling instrument optimization, calibration standardization, and improved sensitivity for <200nm particles.

DOI: 10.1117/12.3097828

Authors: Martin Poinsinet de Sivry-Houle, Ton G. van Leeuwen, Edwin van der Pol

Institutions: Amsterdam University Medical Centers, Cancer Center Amsterdam, Amsterdam Cardiovascular Sciences, University of Amsterdam

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W7115688580

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