Work

Rethinking Potassium Management in Chronic Kidney Disease—A Modern Approach

Year: 2025
Type: article
Abstract: Potassium homeostasis is impaired in patients with chronic kidney disease (CKD) due to alterations in physiological mechanisms and use of agents that modulate the renin angiotensin aldosterone system (RAAS) to slow CKD progression and reduce cardiovascular risk. In recent years, a new paradox has emerged: while dietary potassium restriction has been dogmatically recommended to prevent hyperkalemia, emerging evidence suggests that a more liberated potassium intake may offer potential benefits, particularly in patients with early CKD. This has prompted a paradigm shift towards a more individualized approach to the management of hyperkalemia in CKD. This review aims to provide an overview of the latest management strategies for hyperkalemia in CKD and to summarize the current literature including publications and guidelines recommendations with respect to dietary potassium intake and use of potassium salt substitutes.
Authors: Zheng Xi Kog, Ivan Wei Zhen Lee, Swee Ping Teh
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W7115689183
FWCI: 1.215
Cites: 129
Cited by: 2
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