Work

Nanorobotics in cancer care: innovation without translation?

Year: 2025

Type: article

Abstract: Cancer remains a leading global health burden, with approximately 19.3 million new cases reported worldwide. Limitations of conventional therapies have accelerated interest in nanobots as precision tools for cancer diagnosis and treatment. Their nanoscale dimensions allow targeted drug delivery, reduced systemic toxicity, and enhanced therapeutic efficiency, including hyperthermia-based interventions. Advanced nanobot designs, such as isotope-labeled nanocarbon constructs, three-dimensional DNA nanobots, DNA-origami carriers, and magnetically propelled systems, demonstrate promising capabilities in biomarker detection, controlled drug release, and tumor-specific coagulation. However, despite these innovations, significant translational challenges persist, including safety concerns, off-target effects, and difficulties in external magnetic control. Bridging these gaps will require robust regulatory frameworks, improved nano-tumor biology insights, scalable manufacturing, and the integration of artificial intelligence-driven personalization. Addressing these issues will be pivotal for the clinical incorporation of nanobots in cancer therapy.

Source: Annals of Medicine and Surgery

DOI: 10.1097/ms9.0000000000004543

Authors: Hira Tariq, Muhammad Shahid Mehmood, Fatima Hajj

Institutions: University of the Punjab, University of Agriculture Faisalabad, Lebanese University

Language: English

Topic: Micro and Nano Robotics

Subfield: Condensed Matter Physics

Field: Physics and Astronomy

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,850