The Serum Lipid Profile of Hypertensive Patients in Isiala Mbano, Imo State, Nigeria
Year: 2025
Type: article
Study design: Observational Study
Abstract: This research assessed the serum lipid profiles in patients with hypertension and explored their association with hypertension in Isiala Mbano, Imo State, Nigeria. A total of 127 participants, both male and female, aged 25 years and above, were recruited and divided into hypertensive (n = 80) and normotensive (n = 47) cohorts. Hypertension was identified based on the World Health Organization (WHO) guidelines after taking three consecutive blood pressure readings. Venous blood samples (5 mL) were collected in a sterile manner into plain tubes for biochemical evaluation. Serum concentrations of Total cholesterol (TC), Triglycerides (TG), High-density lipoprotein (HDL) cholesterol, and Low-density lipoprotein (LDL) cholesterol were measured using standardized enzymatic colorimetric techniques. TG exhibited a moderate positive correlation with both TC and HDL (p < 0.001). TC showed a strong positive correlation with HDL and LDL and a moderate positive correlation with TG (all p < 0.001). HDL presented a moderate positive correlation with TG and LDL (p < 0.001), while LDL demonstrated a moderate positive correlation with HDL and TG (p = 0.001). No noteworthy correlation was found between TG and LDL. The hypertensive individuals in this study displayed dyslipidaemic characteristics, with significant positive inter-correlations among different lipid fractions. It is recommended that routine lipid profile evaluations and the early treatment of dyslipidaemia be incorporated into hypertension management to diminish cardiovascular risk.
Authors: Elendu, Melford Uche, Ejiofor, Dominic Chinedu, Iheukwumere, Chinedu Berry, Akubuo, Chigaemezu Remmy-Martin, Okereke, Levi Kelechi
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7116049575
FWCI:
Cites:
Cited by:
Related to: