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Aztreonam–Avibactam as Salvage Therapy in Carbapenem Resistant Klebsiella Pneumoniae Infection with Renal Failure and Neurological Risk

Year: 2025

Type: article

Abstract: We describe the first documented use of Aztreonam–Avibactam under compassionate use for treatment of Metallo-β-lactamase–producing Klebsiella pneumoniae infection in our country. The patient achieved full clinical and microbiological cure without recurrence, and no adverse events occurred. This case underscores the therapeutic potential of Aztreonam–Avibactam in managing multidrug-resistant Gram-negative infections with limited treatment options.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.17979172

Author: Balasubrahmanyam Chandrabhatla1*, Manisha C2, Palepu B Gopal3, Bharath Kumar Pamulapati4*, Amitha Gade5

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7116062901

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