Work

Engineered ω-Transaminase Enables Remote Stereocontrol in the Synthesis of Chiral Pharmaceutical N-Heterocyclic Amines with Nonadjacent Stereocenters

Year: 2025

Type: article

Source: ACS Catalysis

DOI: 10.1021/acscatal.5c07044

Authors: Yuanzhen Zhang, Xiaozheng Wang, Xianqi Yin, Tingting Huang, Shuangjun Lin

Institutions: Shanghai Jiao Tong University, State Key Laboratory of Microbial Metabolism

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Science and Technology Commission of Shanghai Municipality, National Key Research and Development Program of China

Awards: G2366729391, G5054290099

OpenAlex ID: W7116076996

FWCI: 1.558

Cites: 68

Cited by: 6

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