Work

The bladder trigone: A sensory organ?

Year: 2025

Type: article

Abstract: The bladder trigone is a distinct anatomical and functional subregion of the urinary bladder, defined by its triangular configuration between the ureteral orifices and the internal urethral orifice. Although traditionally less studied compared to the bladder dome and detrusor body, recent morphological, molecular, and transcriptomic analyses reveal that the trigone is highly specialized. Understanding the trigone’s role in sensory signaling, urinary continence, and pathophysiological conditions such as bladder pain syndrome and vesicoureteral reflux provides a basis for developing therapeutic approaches to treat disorders involving this structure.

Source: Continence

DOI: 10.1016/j.cont.2025.102309

Authors: Karl-Erik Andersson, Anthony Kanai, Bengt Uvelius

Institutions: Lund University, Wake Forest University, University of Pittsburgh, Skåne University Hospital

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $1,800

OpenAlex ID: W7116100545

FWCI: 0.9

Cites: 32

Cited by: 1

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