Work

Total Synthesis of the TIM-1 IgV Domain via N-to-C Serine/Threonine Ligation Enabled by Knorr Pyrazole Synthesis-Mediated Regeneration of Salicylaldehyde Esters

Year: 2025

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c17340

Authors: Xiaolin Cheng, Zhenquan Sun, Hongxiang Wu, Yisa Xiao, Pengfei Shi, Can Li, Jingwen Zeng, Han Liu, Xuechen Li

Institutions: State Key Laboratory of Synthetic Chemistry, University of Hong Kong, Shanghai Institute of Organic Chemistry, Qingdao National Laboratory for Marine Science and Technology, University of Chinese Academy of Sciences, Ocean University of China

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Research Grants Council, University Grants Committee, Innovation and Technology Commission

Awards: G1966852646, Towards total synthesis of glycoproteins, Chemical synthesis and chemical biology studies of HMGB1 proteins with post-translational modifications, G8617824009

OpenAlex ID: W7116656549

FWCI: 1.263

Cites: 55

Cited by: 5

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